Antioxidants,especially Tocotrienol was observed to exhibit anti-cancer activity against breast cancer cells.
Angiogenesiswhich is the process of formation of blood vessels in cancer cells like in your breast cancer promotes cancer cell death to a very great extent.
Apoptosis is the programmed cell death which leads to the death of cancer cells. Tocotrienol induces apoptosis in breast cancer cells by increasing endoplasmic reticulum stress and autophagy thus helping in killing cancer cells.
Cell Proliferation is the process by which cancer cells copy their DNA and divide into more cancer cells during mitosis thus lead to spreading cancer. According to several kinds of research, it has been observed Tocotrienols suppress the proliferation of breast cancer cells by altering the expression of oxidative stress modulatory enzymes GPX, SOD, NQO1, and NQO2.
Chemopreventionand anti-cancer activity against breast cancer have been observed in Tocotrienols both in vitro and in vivo researches.
Lipid Raft Disruption is induced by Gamma-Tocotrienol which encourages anti-proliferative activity in breast cancer cells.